Association of Comorbidities With COVID19

COVID19 is a new emerging, rapidly disseminating disease that consuming most of resources of
efficient healthcare systems, and several hospitals, worldwide, are currently experiencing a
shortage of ICU beds for critically ill patients with COVID-19 pneumonia.

A risk stratification based on clinical, radiological and laboratory parameters seems
necessary in order to better identify those patients who may need hospital and/or ICU
admission.

One of the most alarming clinical parameters in general is the presence comorbidities. The
underlying diseases including hypertension, diabetes mellitus, respiratory system disease and
cardiovascular disease, may be risk factors for severe COVID-19 patients with adverse
outcomes compared with non-severe patients. Obesity is also a risk factor for COVID-19
severity with increased need to mechanical ventilation.

Chronic diseases share several features with infectious disorders, such as the
proinflammatory state, and the attenuation of the innate immune response which may be linked
etiologically to its pathogenesis.

Aim of the study:to assess the impact of comorbidities in patients with diagnosis of Covid-19
on outcome, in order to find the predictors of prolonged hospital stay, need for ICU
admission or poor outcome