Official Title
A Prospective, Longitudinal, Observational Study to Assess the Seroconversion Status of Front Line Health Care Workers and Comparison With the Suspected or Confirmed Cases of COVID-19 Patients at Max Health Care (Project D)
Brief Summary

A large number of Health Care Workers (HCWs) would be potentially getting exposed to COVID19. Some of them would be asymptomatic or may get subclinical symptoms. Our HCW would have higher exposure and possibly higher seroconversion either symptomatic or with clinical symptoms than the general population. This study is aimed to understand the rate of seroconversion states at different stages of exposure. It is crucial to collect baseline immune status and the early immunological changes that might occur in asymptomatic or symptomatic health care workers and to compare that with the suspected or confirmed cases by following them for six weeks.

Detailed Description

This prospective observational, longitudinal study is being conducted at Max Super Specialty
Hospital, Saket, New Delhi. Below mentioned are the study objectives-

Primary Objectives

- To determine the extent of infection in the healthcare workers (HCW) of a tertiary care
hospital in India, by determining the seropositivity

- To compare immune changes that might occur in healthcare workers who are asymptomatic or
symptomatic with the proven positive cases in OPD or IPD at Max hospital.

Secondary Objectives

- To determine the fraction of asymptomatic or subclinical infections

- To understand the seroconversion status at different stages of exposure to front line
HCW

The study population would include all employees of Max Hospitals, Delhi-NCR, who have been
tested for COVID-19. Samples and data of the COVID positive patients admitted in the hospital
will also be collected and OPD patients coming to the hospital for COVID-19 testing will be
one of the study subsets.

Unknown status
COVID-19
Eligibility Criteria

Inclusion Criteria:

- Healthcare workers of Max Hospital, irrespective of age and gender OR

- COVID-19 positive patients admitted in the hospital OR

- Out-patients getting tested for COVID-19

Exclusion Criteria:

- Refusal to give informed consent, or contraindication to venipuncture.

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 80 Years
Countries
India
Locations

Max Super Speciality Hospital, A Unit of Devki Devi Foundation
New Delhi, Delhi, India

Investigator: Samreen Siddiqui, PhD
Contact: 9582865898
samreensiddiqui@maxhealthcare.com

Investigator:

Contacts

Sujeet Jha, MRCP (U.K)
09910609000
sujeet.jha@maxhealthcare.com

Samreen Siddiqui, PhD
09582865898
samreensiddiqui@maxhealthcare.com

Sujeet Jha, MRCP (U.K), Principal Investigator
Max Healthcare Institute Ltd.

Max Healthcare Insititute Limited
NCT Number
Keywords
Seroconversion
Healthcare Workers
Covid-19
MeSH Terms
COVID-19