Official Title
Risk Factors Affected the Duration of Arterial Line Patency in ICU Bound COVID-19 Patients
Brief Summary

The health care system was completely overwhelmed by the SARS-Cov-2 virus, and ICU admissions soared as a result of the ICU doctors' increased workload. A committed crew inserts invasive line procedures to guarantee a secure and efficient performance. When COVID-19 bound patients were followed up on in the second wave, frequent requests for arterial line placement were noted. These critically ill individuals had high rates of thrombosis, which was linked to thrombotic consequences. Many factors, such as patient morbidities, insertion technique, and operational health care trained personnel's qualifications, contribute to the lowering of arterial line patency. Our ICU management committee approved the use of systemic anticoagulation of ICU admitted patients starting on March 21, 2021 in response to an increase in the incidence of thrombosis and pulmonary embolic events in patients with COVID-19 admitted to the ICU in the second wave of the epidemic.

Detailed Description

1. Introduction / Background The number of Coronavirus Disease 2019 (COVID-19) patients
admitted to the intensive care unit has increased, and it has been noted that this pandemic
is linked to high rates of thrombosis, which has exacerbated its effects on those critically
ill patients.

In order to provide a multidisciplinary, safe service for invasive vascular procedures, as
well as endotracheal intubations and the rapid response team (RRT) for quick assessment of
deteriorating patients in the ward who were in need of ICU admission, which was reported
before at a USA institute, we established a dedicated invasive procedure team from
anesthetists during the peak admission of patients with COVID-19 to the ICU.

Invasive vascular access was employed for hemodynamic monitoring and management in patients
undergoing high-risk surgery, especially in patients who were admitted to the intensive care
unit.Different techniques, such as the use of heparinized fluids, are utilized to lower the
incidence of arterial line failure.

Their main goal was to extend the average patency time of 5 to 10 days. When the arterial
line was implanted for more than 2-3 days, the occlusion was documented. One frequent
consequence is a transient arterial blockage.

We observed an upsurge in demand for arterial line insertions either in newly admitted or
existing ICU patients during the COVID crisis. In addition to posing challenges for the ICU
staff member, the repeated insertion of arterial lines raises the patient's risk for ischemia
thrombosis and infectious occurrences in their limbs. However, there aren't many publications
on the risk factors for arterial line blockages in ICU patients with COVID-19.

Our ICU management committee approved the use of systemic anticoagulation of ICU admitted
patients starting on March 21, 2021 in response to an increase in the incidence of thrombosis
and pulmonary embolic events in patients with COVID-19 admitted to the ICU in the second wave
of this epidemic.

This observational study compares patients before and after the implementation of systemic
anti coagulation to examine the effects of the medication on arterial line patency and the
incidence of arterial line failure.

Identifying risk factors for impaired arterial line patency in both groups will be the
secondary outcome.

Completed
SARS-CoV-2 ICU Bound

Procedure: arterial line

arterial line inserted for invasice mointroing and sampling

Eligibility Criteria

Inclusion Criteria:

- Consecutive ICU patients at HMGH Hospital; Hamad Medical Corporation with continuous
invasive monitoring will be enrolled if they met following eligibility criteria:
peripheral artery cannulation with a suitable arterial cannula and a functional
arterial line established after insertion.

Exclusion Criteria:

- Other pateints with COVID-19 NOT ICU bound

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: 80 Years
Countries
Qatar
Locations

HAMAD Medical Corporation
Doha, Qatar

Hamad Medical Corporation
NCT Number
Keywords
SARS-CoV-2
arterial line patency
risk factors
ICU