Official Title
ANalyzing Olfactory Dysfunction Mechanisms In COVID-19
Brief Summary

We aim to understand the mechanism of olfactory dysfunction in COVID-19.

Detailed Description

In December 2019, a new coronavirus causing severe acute respiratory syndrome was described
in Wuhan, China. This virus, later named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), spread worldwide and has been designated a pandemic by the World Health
Organization.

By the beginning of March 2020, several Ear, Nose, Throat societies raised awareness of a
frequent association between coronavirus disease 2019 (COVID-19) and smell disorders.

In the present study, the investigators wish to begin to understand the pathogenesis of
olfactory dysfunction in COVID-19.

Recruiting
SARS-CoV-2

Other: Sampling of tissue

In all groups of participants, tissue from the nasal cavity and olfactory system will be surgically removed

Eligibility Criteria

Inclusion Criteria:

- Deceased hospitalised patients, tested positive or negative for SARS-CoV-2 for patient or
control group respectively

Exclusion Criteria:

- none

Eligibility Gender
All
Eligibility Age
Minimum: N/A ~ Maximum: N/A
Countries
Belgium
Locations

UZ Leuven
Leuven, Vlaams-Brabant, Belgium

Investigator: Laura Van Gerven, Doctor
Contact: +3216336342
laura.vangerven@uzleuven.be

Contacts

Laura Van Gerven
+3216336342
laura.vangerven@uzleuven.be

Marnick Clijsters
+3216336342
marnick.clijsters@kuleuven.be

Laura Van Gerven, Principal Investigator
UZ/KU Leuven

Universitaire Ziekenhuizen KU Leuven
NCT Number
Keywords
hyposmia
anosmia
Olfactory dysfunction
Covid-19
SARS-CoV-2
MeSH Terms
COVID-19