Official Title
Emergency Laparotomies and Outcomes During the COVID-19 Pandemic - a Retrospective Cohort Study
Brief Summary

NLR has previously been observed to correlate with complications in upper GI (1) and colorectal (2) surgery. The investigators sought to assess if a similar correlation can be identified in emergency general surgical patients and if the presence of suspected or confirmed COVID-19 may impact on this. Given the heterogeneity of emergency general surgery the investigators therefore plan to perform a retrospective review of patients having emergency laparotomies only at a single NHS site during COVID-19 pandemic. Assessment of outcomes and Neutrophil:lymphocyte ratio as a predictor of outcomes will be completed. Outcomes will be completed in line with the recent COVIDSurg study criteria (3). The primary outcome is 30-day mortality. Secondary outcomes are 7-day mortality, re-operation, length of stay, post-operative respiratory failure, post-operative ARDS (Acute Respiratory Distress Syndrome), post-operative sepsis and ITU (Intensive Therapy Unit)/HDU (High Dependency Unit) admission.

Completed
COVID-19
Emergency General Surgery

Procedure: Emergency Laparotomy

All adult patients undergoing emergency laparotomy

Eligibility Criteria

Inclusion Criteria:

- Patients undergoing emergency laparotomy (change made due to heterogeneity of
emergency general surgery)

Exclusion Criteria:

- Inherited or acquired immunodeficiency (which may directly skew NLR)

Eligibility Gender
All
Eligibility Age
Minimum: 18 Years ~ Maximum: N/A
Countries
United Kingdom
Locations

Queen's Hospital
Romford, United Kingdom

Barking, Havering and Redbridge University Hospitals NHS Trust
NCT Number
MeSH Terms
COVID-19
Emergencies